Pathogen effector forms a hexameric phosphatase holoenzyme with host core enzyme to promote disease
Jinlong Wang, Hui Li, Wei Dong Sun, Jiuyu Wang, Xiaodong Fang, Xiaoqi Yang, Chao Liu, Gang Sheng, Wenbo Ma, Yanli Wang
This study reveals the structure of a hexameric phosphatase holoenzyme formed by a pathogen effector and host enzyme, showing enhanced stability and virulence function.
bioRxiv · Jun 14, 2025 · PreprintBiophysics