ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining
Huiming Lu, Qin Zhang, Daniel J. Laverty, Andrew C. Puncheon, Mathew M. Augustine, Gareth J Williams, Zachary David Nagel, Benjamin P.C. Chen, Anthony J. Davis
This study identifies ATM phosphorylation of DNA-PKcs at T4102 as critical for stabilizing NHEJ machinery and promoting DSB repair.
Nucleic Acids Research · May 31, 2023Peer-reviewedMolecular Biology