Qin Zhang

The paper investigates the role of VPS28 in triglyceride synthesis through modulation in bovine cells and a mouse model, showing its regulation via the ubiquitination pathway.

This paper develops a machine learning method to quantify ZO-1 changes in RPE cells, improving assay sensitivity for detecting TJ aberrations in AMD-related treatments.

This study identifies protein biomarkers in vitreous humor and plasma that predict diabetic retinopathy progression, with significant changes observed in vitreous samples of PDR patients.

This study uses single-cell long-read sequencing to analyze transcriptomes of ccRCC organoids, identifying novel transcripts and highlighting cell-specific alternative splicing events.

This study identifies GPR37L1 in satellite glial cells as a regulator of pain control through interactions with potassium channels and maresin 1, showing its role in neuropathic pain resolution.

This study identifies ATM phosphorylation of DNA-PKcs at T4102 as critical for stabilizing NHEJ machinery and promoting DSB repair.

The paper develops a computational framework to infer enhancer-gene networks in T helper cells, revealing T-bet expression intensity as critical for Th cell fate.

This study identifies a proteogenomic signature in blood associated with age-related macular degeneration, linking serum proteins to disease severity and progression.

The paper investigates HSC division patterns in mice, finding most divisions are symmetric self-renewing, maintaining HSC output despite age-related decline in differentiation.