Author

Gareth Prosser

NIAID;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Adrian L. SchwaniD· 1 shared Ashish Kumar· 1 shared Christian C. Gruber· 1 shared Christoph Grininger· 1 shared Clifton E. BarryiD· 1 shared Helena I.M. Boshoff· 1 shared Jansy Passiflora SarathyiD· 1 shared Jörg Lichtenegger· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Adrian L. SchwanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Thienothiazolocarboxamides: rapidly cidal agents causing catastrophic thiol collapse in Mycobacterium tuberculosis.

Sangmi Oh, Gareth Prosser, Helena I.M. Boshoff, Simon Richard Green, Neha Quadir, Jose Santinni O. Roma, Ashish Kumar, Nilesh Mukundan, Sarah Hanson, Jansy Passiflora Sarathy, Kirsteen I Buchanan, Peter C. Ray, Paul G. Wyatt, Thomas R. Ioerger, Adrian L. Schwan, , Clifton E. Barry

This paper identifies thienothiazolocarboxamides as rapidly cidal antituberculosis agents that cause thiol collapse in Mycobacterium tuberculosis through EthA-mediated activation.

bioRxiv · Nov 9, 2026 · PreprintMicrobiology

M. tuberculosis meets European Lead Factory - identification and structural characterization of novel Rv0183 inhibitors using X-ray crystallography

Lina Riegler-Berket, Laura Gödl, Nakia Polidori, Philipp Aschauer, Christoph Grininger, Gareth Prosser, Jörg Lichtenegger, Theo Sagmeister, Lena Parigger, Christian C. Gruber, Norbert Reiling, Monika Oberer

This study identifies and characterizes novel Rv0183 inhibitors using high-throughput screening and X-ray crystallography, demonstrating species-selective inhibition against Mycobacterium tuberculosis.

bioRxiv · Jun 12, 2025Biochemistry