Cancer BiologybioRxivPreprint
Exosome-mediated MIR211 modulates tumor microenvironment via the DUSP6-ERK5 axis and contributes to BRAFV600E inhibitor resistance in melanoma.
Bongyong Lee, Anupama Sahoo, Junko Sawada…·Ranjan J. Perera
This study shows MIR211 promotes melanoma growth and resistance to BRAF inhibitors by modulating the DUSP6-ERK5 axis via exosome transfer in the tumor microenvironment.