Identification of Cryptococcus neoformans capsule-associated protein antigens that mediate B cell-dependent vaccine protection in mice and elicit antibody responses in humans with cryptococcosis
Maureen M. Hester, Diana Carlson, Lorena V. N. Oliveira, Zachary Hastings, Satya Sahu, Jessica Hargarten, Seher Anjum, Gary R. Ostroff, Peter R. Williamson, Charles A. Specht, Stuart M. Levitz
This study identifies Blp4 as a Cryptococcus neoformans antigen that elicits B cell-dependent protective immunity in mice and antibody responses in human cryptococcosis survivors.
bioRxiv · Nov 3, 2026 · PreprintImmunology