BiochemistryNucleic Acids ResearchPeer-reviewed
High-throughput determination of RNA tertiary contact thermodynamics by quantitative DMS chemical mapping
B. W. Lange, Ricardo G. Gil, Gavin S Anderson, Joseph David Yesselman
This paper introduces qDMS-MaPseq, a high-throughput method to measure RNA tertiary contact thermodynamics using DMS chemical mapping, showing strong correlation with specialized instruments.