Cell BiologybioRxivPreprint
A dynamic control of human telomerase holoenzyme
Mohammed E. Sayed, Ao Cheng, Gaya Yadav…·Qiu-Xing Jiang
The paper demonstrates that human telomerase holoenzymes have fast- and slow-acting catalytic sites that become inactive after two rounds of catalysis, and can be reactivated by intracellular factors.
DOI 10.1101/525733