Evaluation of Alphafold modeling for elucidation of nanobody-peptide epitope interactions
Shivani Sachdev, Swarnali Roy, Shubhra Jyoti Saha, Gengxiang Zhao, Rashmi Kumariya, Brendan A. Creemer, Rui Ming Yin, Brian G. Pierce, Carole A. Bewley, Ross W. Cheloha
This study evaluates AlphaFold's ability to model nanobody-peptide interactions, finding moderate success in some cases but limitations when translating to complex contexts.
Journal of Biological Chemistry · May 21, 2025Peer-reviewedBiochemistry