Author

Swarnali Roy

National Institutes of HealthORCID 0009-0006-7449-6776Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Ross W. ChelohaiD· 2 shared Shivani SachdeviD· 2 shared Brendan A. Creemer· 1 shared Brian G. PierceiD· 1 shared Carole A. BewleyiD· 1 shared Gengxiang Zhao· 1 shared Rashmi KumariyaiD· 1 shared Rui Ming YiniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

Ross W. ChelohaORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedMay 21, 2025

Evaluation of Alphafold modeling for elucidation of nanobody-peptide epitope interactions

Shivani Sachdev, Swarnali Roy, Shubhra Jyoti Saha…·Ross W. Cheloha

This study evaluates AlphaFold's ability to model nanobody-peptide interactions, finding moderate success in some cases but limitations when translating to complex contexts.

8 citations

protein structuredeep learning

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Pharmacology & ToxicologybioRxivPreprintMar 7, 2025

Nanobody-based conjugates targeting small molecule-binding GPCRs and exhibiting logic-gated signaling

Shivani Sachdev, Swarnali Roy, Ross W. Cheloha

This paper develops bitopic conjugates targeting GPCRs that enable logic-gated signaling by activating receptor pairs.

1 citation

proteomicsexperimental assay

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