Genome-wide patterns of gene expression in a wild primate indicate species-specific mechanisms associated with tolerance to natural simian immunodeficiency virus infection
Noah D. Simons, Geeta N. Eick, María José Ruiz‐López, David Hyeroba, Patrick A. Omeja, Geoffrey Weny, Huiyuan Zheng, Anupama Shankar, Simon D. W. Frost, James Holland Jones, Colin A. Chapman, William M. Switzer, Tony L. Goldberg, Kirstin N. Sterner, Nelson Ting
The paper analyzes gene expression in wild Ugandan red colobus to show SIV infection does not cause chronic immune activation and identifies upregulation of CD101 as a potential tolerance mechanism.
Genome Biology and Evolution · May 9, 2019Peer-reviewedGenomics