Author

George Mitra

Regeneron (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:variant effect prediction· 2 Assay:whole-exome sequencing· 2 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Adam E. LockeiD· 3 shared Adam J. Mansfield· 3 shared Alan R. ShuldineriD· 3 shared Alexander E. LopeziD· 3 shared Anthony MarckettaiD· 3 shared Boris BoutkoviD· 3 shared Evan K. MaxwelliD· 3 shared Gonçalo R. AbecasisiD· 3 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Adam E. LockeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genomic ascertainment of CHEK2-related cancer predisposition

Sun Young Kim, Jung Kim, Mark Ramos, Jeremy S. Haley, Diane T. Smelser, H. Shanker Rao, Uyenlinh L. Mirshahi, Katherine L. Nathanson, Barry I. Graubard, Hormuzd A. Katki, David J. Carey, Douglas R. Stewart, Aris Baras, Gonçalo R. Abecasis, Adolfo A. Ferrando, , Arden Moscati

This study quantifies cancer risk and penetrance in CHEK2 heterozygotes using genomic data from two large biobanks, finding increased risks for several cancers and younger age of onset.

JAMA Network Open · Dec 15, 2025Peer-reviewedGenetic & Genomic Medicine

A deep catalog of protein-coding variation in 985,830 individuals

Kathie Sun, Xiaodong Bai, Siying Chen, Suying Bao, Manav Kapoor, Chuanyi Zhang, Joshua Backman, Tyler Joseph, Evan K. Maxwell, George Mitra, Alexander Gorovits, Adam J. Mansfield, Boris Boutkov, Sujit Gokhale, Lukas Habegger, , Suganthi Balasubramanian

This paper presents the largest catalog of human protein-coding variation from 985,830 individuals, identifying rare variants and their functional implications for precision medicine.

bioRxiv · May 9, 2023 · PreprintGenetics

Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease

Julie E. Horowitz, Jack A. Kosmicki, Amy Damask, Deepika Sharma, Genevieve H. L. Roberts, Anne E. Justice, Nilanjana Banerjee, Marie V. Coignet, Ashish Yadav, Joseph B. Leader, Anthony Marcketta, Danny S. Park, Rouel Lanche, Evan K. Maxwell, Spencer C. Knight, , Arden Moscati

The paper identifies a rare variant that lowers ACE2 expression and reduces COVID-19 risk, and develops a genetic risk score predicting severe disease.

Nature Genetics · Mar 3, 2022Peer-reviewedGenetic & Genomic Medicine