Knockdown of astrocytic monocarboxylate transporter 4 (MCT4) in the motor cortex leads to loss of dendritic spines and a deficit in motor learning
Adam J. Lundquist, George N. Llewellyn, Susan H. Kishi, Nicolaus A. Jakowec, Paula M. Cannon, Giselle Maria Petzinger, Michael Walter Jakowec
This study shows that knocking down astrocytic MCT4 in the motor cortex impairs motor learning and reduces dendritic spines and neuronal activity.
Molecular Neurobiology · Nov 25, 2021Peer-reviewedNeuroscience