Hexosyl transfer via a covalent intermediate within a dual retaining and inverting enzyme
Mert Sagiroglugil, Beatriz Piniello Castillo, Miron A. Leanca, Eduardo S. Kitano, Courtney J. Mycroft‐West, Georgios Papadakis, Maria A. Gafitescu, Shabaz Mohammed, Benjamin G. Davis, Carme Rovira, Liang Wu
This study reveals a covalent mechanism in a bifunctional glycosyltransferase for hexosyl transfer and reports a novel self-priming function for polymerization.
bioRxiv · Oct 21, 2026 · PreprintBiochemistry