Author

Mert Sagiroglugil

Universitat de BarcelonaORCID 0000-0002-4714-3717Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Carme RoviraiD· 2 shared André OharaiD· 1 shared Anna CioceiD· 1 shared Beatriz Piniello Castillo· 1 shared Benjamin G. DavisiD· 1 shared Benjamin SchumanniD· 1 shared Carolyn Ruth BertozziiD· 1 shared Courtney J. Mycroft‐WestiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Carme RoviraORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 21, 2026

Hexosyl transfer via a covalent intermediate within a dual retaining and inverting enzyme

Mert Sagiroglugil, Beatriz Piniello Castillo, Miron A. Leanca…·Liang Wu

This study reveals a covalent mechanism in a bifunctional glycosyltransferase for hexosyl transfer and reports a novel self-priming function for polymerization.

DOI 10.64898/2026.10.20.760405

experimental assay

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BiochemistryJournal of the American Chemical SocietyPeer-reviewedJun 30, 2026

Iterative Bump-and-hole engineering creates a bioorthogonal reporter for N-acetylglucosaminyltransferase I

Liu Yu, Saskia Pieters, Ganka Bineva‐Todd…·Benjamin Schumann

The paper develops a bioorthogonal reporter for MGAT1 by iteratively engineering a UDP-GlcNAc analog with a chemical tag, enabling specific substrate incorporation in mammalian cells.

3 citationstop 3%

humanproteomics

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