Author

Germain C. M. Alas

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 1

Frequent Co-Authors

Alexander R. ParedeziD· 3 shared Han-Wei ShihiD· 3 shared

Activity by Year

2022-2024 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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3 shared papersDevelopmental Biology

Alexander R. ParedezORCID

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3 papers

Recent·Most cited

Unraveling the Role of cAMP Signaling in Giardia: Insights into PKA-Mediated Regulation of Encystation and Subcellular Interactions

Han-Wei Shih, Germain C. M. Alas, Alexander R. Paredez

This study investigates the role of cAMP signaling in Giardia, focusing on PKA-mediated regulation of encystation and subcellular interactions using Split-Halo technology.

mSphere · Oct 30, 2024Peer-reviewedDevelopmental Biology

Encystation stimuli sensing mediated by adenylate cyclase AC2-dependent cAMP signaling in Giardia

Han-Wei Shih, Germain C. M. Alas, Alexander R. Paredez

The paper shows that AC2-dependent cAMP signaling mediates encystation in Giardia lamblia in response to stimuli like bile and alkaline pH.

bioRxiv · Apr 10, 2023 · PreprintDevelopmental Biology

A cell cycle-dependent GARP-like transcriptional repressor regulates the initiation of differentiation in Giardia lamblia

Han-Wei Shih, Germain C. M. Alas, Alexander R. Paredez

This paper identifies GLP4, a GARP-like transcriptional repressor, as a key regulator of encystation initiation in Giardia lamblia by repressing MYB2 and encystation-specific genes during the G1+S phase of the cell cycle.

Proceedings of the National Academy of Sciences · May 25, 2022Peer-reviewedDevelopmental Biology