Han-Wei Shih

This study identifies an ATG8-independent autophagy-like pathway in Giardia lamblia regulated by GlRac, showing structural and functional similarities to canonical autophagy despite lacking most ATG genes.

This study investigates the role of cAMP signaling in Giardia, focusing on PKA-mediated regulation of encystation and subcellular interactions using Split-Halo technology.

The paper shows that AC2-dependent cAMP signaling mediates encystation in Giardia lamblia in response to stimuli like bile and alkaline pH.

This paper identifies GLP4, a GARP-like transcriptional repressor, as a key regulator of encystation initiation in Giardia lamblia by repressing MYB2 and encystation-specific genes during the G1+S phase of the cell cycle.