Repeat expansion in a Fragile X model is independent of double strand break repair mediated by Pol θ, Rad52, Rad54l or Rad54b
Bruce E. Hayward, Geum-Yi Kim, Carson J. Miller, Cai McCann, Megan G. Lowery, Richard Dean Wood, Karen Usdin
This study investigates the role of double-strand break repair proteins in repeat expansion in Fragile X disease models and finds that loss of Pol θ, Rad52, Rad54l, or Rad54b does not significantly affect expansion.
bioRxiv · Nov 5, 2024 · PreprintGenetics