The Phosphate-Specific Transport System Gene pstA1 Contributes to Rifampin Tolerance in Mycobacterium tuberculosis
Carina Danchik, G. V. Anoushka Chinmayi, Gi Yong Lee, Subramanian Mahadevan, Joel S. Bader, Hyungjin Eoh, Petros C. Karakousis
This study identifies the phosphate transport gene pstA1 as a key contributor to rifampin tolerance in Mycobacterium tuberculosis, showing that its deletion reduces bacterial survival during antibiotic treatment.
The Journal of Infectious Diseases · Sep 22, 2026Peer-reviewedMicrobiology