Ancestry-specific rewiring of BCR-MAPK signaling in sarcoidosis B cells
Christopher M. Dunn, Caleb Watkins, Gideon B Hallum, Nathan P. Pezant, Astrid Rasmussen, Patrick M. Gaffney, Harini Bagavant, Umesh S. Deshmukh, Courtney G. Montgomery
This study uses single-cell RNA sequencing to show ancestry-specific B cell signaling changes in sarcoidosis, with more differentially expressed genes in African ancestry patients.
bioRxiv · Apr 22, 2026 · PreprintImmunology