Umesh S. Deshmukh

This paper identifies a feedback mechanism where Vγ1.1Vδ6.3 T cells are reprogrammed into ILC1-like cells to restrain autoimmune pathology.

This study uses single-cell RNA sequencing to show ancestry-specific B cell signaling changes in sarcoidosis, with more differentially expressed genes in African ancestry patients.

The paper shows that female UM-HET3 mice develop age-related autoimmunity and sialadenitis with a female sex bias, potentially reflecting benign autoimmunity linked to aging.

This study identifies dysregulated Ca2+ signaling and mitochondrial dysfunction in a mouse model of early Sjogrens syndrome, leading to reduced fluid secretion.

This study shows that aging in mice leads to B cell infiltration and autoantibody production in salivary glands, resembling Sjögren's disease features.