Author

Samah Houmam

Oklahoma Medical Research FoundationORCID 0000-0002-8036-321XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Casandra Salinas-SalinasiD· 4 shared Heather C. RiceiD· 4 shared Dominika SiodłakiD· 2 shared Dylan Barber· 2 shared Kriti Shukla· 2 shared Yvonne M. ThomasoniD· 2 shared Anna FaakyeiD· 1 shared Courtney G. MontgomeryiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersNeuroscience

Casandra Salinas-SalinasORCID

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4 papers

Recent·Most cited

Amyloid precursor protein interacts with the mitochondrial phosphatase PGAM5 and regulates mitochondrial respiration

Kriti Shukla, Z. Zhang, Kendra S. Plafker, Satoshi Matsuzaki, Casandra Salinas-Salinas, Yvonne M. Thomason, Samah Houmam, Dylan Barber, Anna Faakye, Kenneth Michael Humphries, Scott M. Plafker, Jialing Lin, Heather C. Rice

This study identifies an interaction between APP and PGAM5, showing that APP regulates mitochondrial respiration by modulating Keap1-Nrf2 signaling.

bioRxiv · Mar 12, 2026 · PreprintNeuroscience

sAPPalpha inhibits neurite outgrowth in primary mouse neurons via GABA B Receptor subunit 1a

Dylan Barber, Casandra Salinas-Salinas, Samah Houmam, Kriti Shukla, Heather C. Rice

The paper shows sAPPalpha inhibits neurite outgrowth in mouse neurons via GABABR1a, with sAPP requiring the extension domain to bind GABABR1a and suppress axon growth.

eNeuro · Feb 1, 2026Peer-reviewedNeuroscience

Oligodendrocytes show enriched expression of amyloid precursor protein and GABA B receptor isoform 1a

Samah Houmam, Dominika Siodłak, Meena Seshadri, Gideon B Hallum, Nathan P. Pezant, David R. Stanford, Casandra Salinas-Salinas, Yvonne M. Thomason, Courtney G. Montgomery, Heather C. Rice

The paper shows GABABR1a is most expressed in oligodendrocytes and APP is most expressed in oligodendrocytes among five brain cell types.

bioRxiv · Nov 25, 2025 · PreprintNeuroscience

Protocol to isolate oligodendrocytes, microglia, endothelial cells, astrocytes, and neurons from a single mouse brain using magnetic-activated cell sorting

Samah Houmam, Dominika Siodłak, Kevin D. Pham, Casandra Salinas-Salinas, Sarah R. Ocañas, Willard M. Freeman, Heather C. Rice

This paper describes a protocol for isolating five specific brain cell types from a single mouse brain using magnetic-activated cell sorting.

bioRxiv · Aug 8, 2025 · PreprintNeuroscience