The Host Cell ViroCheckpoint: Identification and Pharmacologic Targeting of Novel Mechanistic Determinants of Coronavirus-Mediated Hijacked Cell States
Pasquale Laise, Gideon Bosker, Xiaoyun Sun, Yao Shen, Eugene F. Douglass, Charles Karan, Ronald B. Realubit, Sergey Pampou, Andrea Califano, Mariano J. Alvarez
The paper identifies host cell Master Regulator proteins hijacked by SARS-CoV and identifies drugs that can target these proteins to disrupt viral replication.
bioRxiv · May 12, 2020 · PreprintSystems Biology