Systematic elucidation and pharmacologic targeting of non-oncogene dependencies in imatinib-resistant gastrointestinal stromal tumor
Prabhjot Singh Mundi, Adina Grunn, Arsenije Kojadinovic…·Andrea Califano
This study identifies non-oncogene dependencies in imatinib-resistant GIST using network-based methods and validates six drugs that reverse MR activity in preclinical models.