Comprehensive analysis of prime editing outcomes in human embryonic stem cells
Omer Habib, Gizem Habib, Gue‐Ho Hwang, Sangsu Bae
This paper tests prime editing in human pluripotent stem cells, showing it can induce various genetic modifications and correct disease mutations without off-target effects from the reverse transcriptase domain.
Nucleic Acids Research · Dec 21, 2021Peer-reviewedGenomics