The pro-, but not anti-nociceptive effects of Cannabidiol depend on Trpa1b in larval Zebrafish
Bryce Lecamp, Quinn Bianucci, Sidhant Rauniyar, Gloria Shen, Kali Esancy, Benjamin Bruce Land, Ajay K. Dhaka
This study shows CBD has both anti- and pro-nociceptive effects in larval zebrafish, with Trpa1b mediating the pro-nociceptive effects while CB1/CB2 and Trpv1 may mediate analgesia.
Journal of Neuroscience · Mar 3, 2026Peer-reviewedNeuroscience