Robust three-dimensional expansion of human adult alveolar stem cells and SARS-CoV-2 infection
Jeonghwan Youk, Taewoo Kim, Kelly V. Evans, Young-Il Jeong, Yongsuk Hur, Seon Pyo Hong, Je Hyoung Kim, Kijong Yi, Su Yeon Kim, Kwon Joong Na, Thomas Bleazard, Ho Min Kim, Natasha Ivory, Krishnaa T. Mahbubani, Kourosh Saeb-Parsy, , Joo-Hyeon Lee
This study develops a 3D culture model of human alveolar type 2 cells to study SARS-CoV-2 infection and reveals rapid viral replication and immune response.
Cell Stem Cell · Dec 1, 2020Peer-reviewedCell Biology