Author
Korea Advanced Institute of Science and TechnologyORCID 0000-0002-6761-3958Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Yohan An, Ji‐Hyun Lee, Joonoh Lim…·Young Seok Ju
This study shows APOBEC3A, not APOBEC3B, causes significant mutagenesis in human gastric epithelium through whole-genome sequencing of organoids with inducible APOBEC3A or APOBEC3B.
Chang Hyun Nam, Jeonghwan Youk, Jeong Yeon Kim…·Young Seok Ju
The paper analyzes somatic L1 retrotranspositions in single-cell genomes from normal human tissues, finding high prevalence in colorectal cells and revealing epigenetic mechanisms driving retrotransposition.
Min-Su Kang, Hee Young Na, Soomin Ahn…·Ho‐Seong Han
This study traces the evolutionary paths of gallbladder adenocarcinomas, showing subclonal diversification and selection from precancerous lesions to metastatic tumors.
Seongyeol Park, Nanda Maya Mali, Ryul Kim…·Young Seok Ju
This study uses somatic mutations to reconstruct cellular phylogenetic trees and analyze clonal dynamics in early human embryogenesis.
Jeonghwan Youk, Hyun Woo Kwon, Joonoh Lim…·Young Seok Ju
The paper investigates the mutational impact of ionizing radiation on normal cells and confirms these signatures in IR-induced cancers.
Jeonghwan Youk, Taewoo Kim, Kelly V. Evans…·Joo-Hyeon Lee
This study develops a 3D culture model of human alveolar type 2 cells to study SARS-CoV-2 infection and reveals rapid viral replication and immune response.