Author

Kourosh Saeb-Parsy

National Institute for Health and Care Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ahmad Miremadi· 1 shared Benjamin A. HalliD· 1 shared Byeong-Sun Choi· 1 shared Charlotte CassieiD· 1 shared Christopher M Jones· 1 shared Curtis W Frank· 1 shared Da Yoon No· 1 shared Daniel H. JacobsoniD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

Ahmad Miremadi

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Author profile →

4 papers

Recent·Most cited

Polyclonal and clonal organoid models of Barrett oesophagus and oesophageal adenocarcinoma reveal heterogeneity in progression and therapy response

Daniel H. Jacobson, Dylan Peter McClurg, Yibing Wang, Emily Black, Charlotte Cassie, Tik Shing Cheung, Hannah Coles, Ginny Devonshire, SriGanesh Jammula, Benjamin A. Hall, Xiaodun Li, Ahmad Miremadi, Krishnaa T. A. Mahbubani, Massimiliano di Pietro, Kourosh Saeb-Parsy, , Lizhe Zhuang

The paper generates organoid models of Barrett oesophagus and oesophageal adenocarcinoma to study disease progression and therapy response.

bioRxiv · Oct 31, 2026 · PreprintCancer Biology

BRIDGE-AD reveals Alzheimer's disease effectors through interpretable large-scale omics integration

Greta Baltušytė, Jonas Cerneckis, Harry Convey, Guoqiang Sun, Zyrille C. E. Abela, Miguel Ramirez, Daniel Wang, Guihua Sun, Tao Zhou, David R. Spring, Kourosh Saeb-Parsy, Yanhong Shi, Namshik Han

BRIDGE-AD integrates multimodal AD datasets to prioritize disease effectors, identifying 19 functional clusters and validating SCARB2 as a novel candidate.

bioRxiv · Sep 25, 2026 · PreprintBioinformatics

Robust three-dimensional expansion of human adult alveolar stem cells and SARS-CoV-2 infection

Jeonghwan Youk, Taewoo Kim, Kelly V. Evans, Young-Il Jeong, Yongsuk Hur, Seon Pyo Hong, Je Hyoung Kim, Kijong Yi, Su Yeon Kim, Kwon Joong Na, Thomas Bleazard, Ho Min Kim, Natasha Ivory, Krishnaa T. Mahbubani, Kourosh Saeb-Parsy, , Joo-Hyeon Lee

This study develops a 3D culture model of human alveolar type 2 cells to study SARS-CoV-2 infection and reveals rapid viral replication and immune response.

Cell Stem Cell · Dec 1, 2020Peer-reviewedCell Biology

Conversion of iPS derived hepatic progenitors into scalable, functional and developmentally relevant human organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold engineered from collagen-coated pores of defined size

Soon Seng Ng, Kourosh Saeb-Parsy, Joe M Segal, Maria Paola Serra, Samuel J I Blackford, Marta Horcas Lopez, Da Yoon No, Curtis W Frank, Nam Joon Cho, Hiromitsu Nakauchi, Jeffrey S Glenn, S Tamir Rashid

This paper develops a bioengineered scaffold to generate functional human liver organoids from iPSCs, showing improved morphology, gene expression, and functionality compared to 2D and 3D controls.

bioRxiv · Apr 6, 2018 · PreprintBioengineering