Mycobacterium avium subspecies paratuberculosis targets M cells in enteroid-derived monolayers through interactions with β1 integrins
Grace Baruta, Kyle L. Flannigan, Laurie A. Alston, Andrew J. Thorne, Hong Zhang, Jeroen De Buck, Pina Colarusso, Simon Andrew Hirota
This study identifies M cells as the primary target of Mycobacterium avium subspecies paratuberculosis (MAP) entry into the small intestinal epithelium, mediated by fibronectin-bridging interactions with β1 integrins.
American Journal of Physiology-Gastrointestinal and Liver Physiology · Mar 20, 2025Peer-reviewedCell Biology