Author

Andrew J. Thorne

University of CalgaryORCID 0009-0009-1519-6126Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Akanksha BansaliD· 1 shared Alex Gao· 1 shared Amandah Necker‐BrowniD· 1 shared Andrei Georgescu· 1 shared Anthony N. GerberiD· 1 shared Cora Kooi· 1 shared Grace Baruta· 1 shared Hong ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Akanksha BansalORCID

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2 papers

Recent·Most cited

Molecular BiologyPLoS ONEPeer-reviewedDec 8, 2025

Inflammatory cytokines promote interferon regulatory factor (IRF) transcriptional activity in human pulmonary epithelial cells through the induction of IRF1 by nuclear factor-κB

Amandah Necker‐Brown, Mahmoud Mostafa, Andrei Georgescu…·Robert Charles Newton

This study investigates how inflammatory cytokines like IL-1β and TNF induce IRF1 expression in human pulmonary epithelial cells through NF-κB activation, revealing potential mechanisms in glucocorticoid-resistant diseases.

3 citations

humanbulk RNA-seq

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Cell BiologyAmerican Journal of Physiology-Gastrointestinal and Liver PhysiologyPeer-reviewedMar 20, 2025

Mycobacterium avium subspecies paratuberculosis targets M cells in enteroid-derived monolayers through interactions with β1 integrins

Grace Baruta, Kyle L. Flannigan, Laurie A. Alston…·Simon Andrew Hirota

This study identifies M cells as the primary target of Mycobacterium avium subspecies paratuberculosis (MAP) entry into the small intestinal epithelium, mediated by fibronectin-bridging interactions with β1 integrins.

4 citations

mouseproteomics

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