Evaluating anaesthetics for improving scientific research and welfare using larval zebrafish
Sylvia Dimitriadou, Mhairi Miller, Ali Pilehvar, Lynne U. Sneddon, Jessica L. Bamsey, Damilola Hogan-Bassey, Maciej Trznadel, Jonathan S. Ball, Aya Takesono, Courtney Hillman, Hannah Rickard, Grace Popplewell, Jenna Corcoran, Tetsuhiro Kudoh, Charles R. Tyler, Matthew J. Winter
The paper evaluates six anaesthetics for their efficacy and tolerability in larval zebrafish, identifying MS222 and quinaldine sulfate as most suitable for deep anaesthesia and etomidate for cardiovascular studies.
bioRxiv · Oct 6, 2025 · PreprintPhysiology