The Mechanosensitivity of the Regenerative Response in Bone is Retained with Aging in a Mouse Model of Premature Aging.
Neashan Mathavan, Francisco Correia Marques, Graeme R. Paul, Sara Lindenmann, Stefanie Wissmann, Dilara Yilmaz, Gisela Anna Kuhn, Esther Wehrle, Ralph Müller
This study shows that aged bone retains mechanosensitivity, with mechanical loading improving regeneration in a mouse model of premature aging.
bioRxiv · Feb 3, 2026 · PreprintPhysiology