Neashan Mathavan

The paper examines how mechanical loading and pharmacological therapies affect osteocyte lacunar morphology in a mouse osteoporosis model, showing distinct adaptations in lacunar density, volume, and sphericity.

This study shows that aged bone retains mechanosensitivity, with mechanical loading improving regeneration in a mouse model of premature aging.

Spatial μProBe integrates multimodal imaging to analyze spatial gene expression and mechanical environments in musculoskeletal tissues.

This study uses spatial transcriptomics to analyze gene expression in relation to mechanical strain in fracture healing, identifying strain-dependent gene expression patterns.

This study characterizes frailty in PolgA mice, showing sex-specific differences and parallels to human aging.