Author

Gregory J. Hogan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetics· 3 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Research Focus:variant calling· 4 Approach:statistical model· 3 Assay:whole-exome sequencing· 3 Approach:experimental assay· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Clement S. Chu· 3 shared Dale MuzzeyiD· 3 shared Hyunseok Peter KangiD· 3 shared Imran S. HaqueiD· 3 shared Jared Maguire· 3 shared Mark R. Theilmann· 3 shared Peter V. Grauman· 3 shared Diana Jeon· 2 shared

Activity by Year

2017-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetics

Clement S. Chu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Detecting clinically actionable variants in the 3’ exons of PMS2 via a reflex workflow based on equivalent hybrid capture of the gene and its pseudogene

Genevieve M. Gould, Peter V. Grauman, Mark R. Theilmann, Lindsay Spurka, Irving E. Wang, Laura M. Melroy, Robert G. Chin, Dustin Hite, Clement S. Chu, Jared Maguire, Gregory J. Hogan, Dale Muzzey

This paper develops a reflex workflow using NGS and LR-PCR to accurately detect clinically actionable variants in PMS2 exons while distinguishing them from pseudogene variants.

BMC Medical Genetics · Sep 29, 2018Peer-reviewedGenomics

Development and validation of an expanded carrier screen that optimizes sensitivity via full-exon sequencing and panel-wide copy-number-variant identification

Gregory J. Hogan, Valentina S. Vysotskaia, Stefanie Seisenberger, Peter V. Grauman, Kyle A. Beauchamp, Kevin R. Haas, Sun Hae Hong, David Jennions, Diana Jeon, Shera Kash, H. Henry Lai, Laura M. Melroy, Mark R. Theilmann, Clement S. Chu, Saurav Guha, , Dale Muzzey

This paper validates an expanded carrier screen with high sensitivity and specificity, showing significant improvements in detecting fetal disease risk through CNV calling and challenging conditions.

Clinical Chemistry · May 14, 2018Peer-reviewedGenetics

Systematic Design and Comparison of Expanded Carrier Screening Panels

Kyle A. Beauchamp, Dale Muzzey, Kenny K. Wong, Gregory J. Hogan, Kambiz Karimi, Sophie I. Candille, Nikita N. Mehta, Rebecca Mar‐Heyming, Kristjan Eerik Kaseniit, Hyunseok Peter Kang, Eric A. Evans, James D. Goldberg, Gabriel A. Lazarin, Imran S. Haque

The paper evaluates methods for designing expanded carrier screening panels and finds that full-exon sequencing outperforms targeted genotyping in detecting affected fetuses.

Genetics in Medicine · Jun 22, 2017Peer-reviewedGenetics

Development and validation of a 36-gene sequencing assay for hereditary cancer risk assessment

Valentina S. Vysotskaia, Gregory J. Hogan, Genevieve M. Gould, Xin Wang, Alex D. Robertson, Kevin R. Haas, Mark R. Theilmann, Lindsay Spurka, Peter V. Grauman, Henry H. Lai, Diana Jeon, Genevieve Haliburton, Matt Leggett, Clement S. Chu, Kevin Iori, , Imran S. Haque

The paper develops and validates a 36-gene sequencing assay for hereditary cancer risk assessment, showing 100% sensitivity and high specificity across mutation types.

PeerJ · Feb 23, 2017Peer-reviewedGenetics