Author

H. Henry Lai

Washington University in St. LouisORCID 0000-0003-2691-994XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Aaron D. MickleiD· 1 shared Clement S. Chu· 1 shared Dale MuzzeyiD· 1 shared David Jennions· 1 shared Diana Jeon· 1 shared Eric A. EvansiD· 1 shared Graydon B. GereauiD· 1 shared Gregory J. Hogan· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Aaron D. MickleORCID

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2 papers

Recent·Most cited

GeneticsClinical ChemistryPeer-reviewedMay 14, 2018

Development and validation of an expanded carrier screen that optimizes sensitivity via full-exon sequencing and panel-wide copy-number-variant identification

Gregory J. Hogan, Valentina S. Vysotskaia, Stefanie Seisenberger…·Dale Muzzey

This paper validates an expanded carrier screen with high sensitivity and specificity, showing significant improvements in detecting fetal disease risk through CNV calling and challenging conditions.

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humanwhole-exome sequencing

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NeuroscienceScientific ReportsPeer-reviewedNov 14, 2017

Optogenetic silencing of primary afferents reduces evoked and ongoing bladder pain

Vijay K. Samineni, Aaron D. Mickle, Jangyeol Yoon…·Robert W. Gereau

This study uses optogenetic inhibition of Nav1.8+ bladder sensory afferents in a mouse model of cystitis to reduce pain and hypersensitivity.

65 citationstop 2%

mouseexperimental assay

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