Chemical tools to define and manipulate interferon-inducible Ubl protease USP18
Griffin J. Davis, Anthony O. Omole, Ye‐Jin Jung, Wioletta Rut, Ronald J. Holewinski, Kiall F. Suazo, Hong‐Rae Kim, Mo Yang, Þorkell Andrésson, Marcin Drąg, Euna Yoo
The paper develops activity-based probes to selectively detect USP18 activity and screen for inhibitors, enabling analysis of USP18's role in disease states.
Nature Communications · Jan 22, 2025Peer-reviewedMolecular Biology