The genetic architecture of trabecular bone score and association with fracture: a genome-wide association and meta-analysis
Haojie Lu, Griffin Tibbitts, Gloria Hoi‐Yee Li, Monika Frysz, Christine W. Lary, Katerina Trajanoska, Nilabhra Rohan Das, C.P.G.M. de Groot, Ching‐Lung Cheung, Natasja M. van Schoor, André Gerardus Uitterlinden, Nathalie van der Velde, Jonathan H. Tobias, Fernando Rivadeneira, David M. Evans, , Carolina Medina‐Gómez
This study identifies 33 genetic variants associated with trabecular bone score (TBS) and finds a potential causal link between TBS and fracture risk independent of bone mineral density.
bioRxiv · Oct 1, 2025 · PreprintGenomics