A tumor-secreted protein utilizes glucagon release to cause host wasting
Guangming Ding, Yingge Li, Cheng Chen, Kai Tan, Yifei Deng, Huiwen Pang, Zhongyuan Wang, Peixuan Dang, Xing Wu, Elisabeth Rushworth, Yufeng Yuan, Zhi‐Yong Yang, Wei Song
This study identifies a tumor-secreted protein that activates a host hormone pathway to induce systemic wasting in both flies and mammals.
Cell Discovery · Feb 9, 2025Peer-reviewedPhysiology