Regulation of neuron-specific gene transcription by stress hormone signalling requires synaptic activity in zebrafish
Helen Eachus, Dheemanth Subramanya, Harriet E. Jackson, Guannyu Wang, Kieran Berntsen, John‐Paul Ashton, Umberto Esposito, Fayaz Seifuddin, Mehdi Pirooznia, Eran Elhaik, Nils Peter Krone, Richard Baines, Marysia Placzek, Vincent T. Cunliffe
This study identifies two distinct GR-regulated transcription pathways in zebrafish brains, showing synaptic activity's role in GR-mediated transcription of aplp1.
bioRxiv · Feb 26, 2020 · PreprintDevelopmental Biology