Fayaz Seifuddin

This study evaluates reproducibility and accuracy of cancer mutation detection using whole-genome and whole-exome sequencing across multiple sequencing centers and bioinformatics pipelines.

The paper identifies autophagic and mitochondrial dysfunctions in SARS-CoV-2 infection through transcriptome profiling and network analysis of cell lines and human samples.

This study evaluates somatic CNV callers using NGS data from 91 samples with varying factors, finding that caller choice and tumor purity significantly impact call quality.

The paper introduces lncRNAKB, a comprehensive knowledgebase of 77,199 human lncRNAs with expression, conservation, and cis-eQTL data from GTEx.

This study identifies two distinct GR-regulated transcription pathways in zebrafish brains, showing synaptic activity's role in GR-mediated transcription of aplp1.

IKAP improves identification of major cell types in single-cell RNA-seq by tuning clustering parameters to enhance differentiation between cell groups.