Presynaptic mitochondria calcium uniporter promotes auditory temporal processing during sustained high-rate activity
This study investigates the role of mitochondrial calcium uniporter (MCU) in synaptic transmission at the auditory nerve endbulb of Held synapse and postsynaptic bushy neurons, finding that MCU is dispensable under low-rate activity but critical for maintaining temporal precision during high-rate activity.
bioRxiv · Jun 25, 2026 · PreprintNeuroscience