Ruili Xie

This study investigates the role of mitochondrial calcium uniporter (MCU) in synaptic transmission at the auditory nerve endbulb of Held synapse and postsynaptic bushy neurons, finding that MCU is dispensable under low-rate activity but critical for maintaining temporal precision during high-rate activity.

This study investigates the role of complement protein C3 in cochlear tissue damage after noise trauma, finding dynamic C3 activation and its involvement in damage recognition and clearance.

The paper examines the distribution of spiral ganglion neuron subtypes along the cochlea and their changes with aging in mice, finding a frequency-dependent pattern and age-related loss of Ic SGNs in the base.

This study examines age-related changes in dendritic morphology and synaptic innervation of bushy neurons in the cochlear nucleus, finding reduced dendritic complexity and altered synaptic input patterns associated with age-related hearing loss.

The paper investigates how different types of spiral ganglion neuron synapses in the cochlear nucleus change during age-related hearing loss, finding that non-calretinin-expressing synapses degenerate more severely.

This study uses linear discriminant analysis to classify neurons in the adult mouse cochlear nucleus based on electrical properties and morphology, revealing distinct clusters of VCN and DCN neurons.