ADP-ribose derived Nuclear ATP is Required for Chromatin Remodeling and Hormonal Gene Regulation
Roni H. G. Wright, Francois LeDily, Daniel Soronellas, Andy Pohl, Jaume Bonet, A. S. Nacht, Guillermo P. Vicent, Michael Wierer, Baldo Oliva, Miguel Beato
The paper shows that nuclear ATP, generated from ADP-ribose via NUDIX5/NUDT5, is essential for hormone-induced chromatin remodeling, gene regulation, and cell proliferation.
bioRxiv · Jun 25, 2014 · PreprintMolecular Biology