Author

Guojin Tang

Nanjing Drum Tower Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Organism:multiple species· 1 Research Focus:protein design· 1 Approach:statistical model· 1

Frequent Co-Authors

Bin ZhengiD· 2 shared Jun QiuiD· 2 shared Peng ZhengiD· 2 shared Lichao LiuiD· 1 shared Lin ChengiD· 1 shared Meimei Duan· 1 shared Shangchen Wang· 1 shared Tianfu Feng· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiophysics

Bin ZhengORCID

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2 papers

Recent·Most cited

Transforming a Fragile Protein Helix into an Ultrastable Scaffold via a Hierarchical AI and Chemistry Framework

Jun Qiu, Guojin Tang, Tianfu Feng, Bin Zheng, Yuanhao Liu, Peng Zheng

This paper designs ultrastable helical proteins using AI and chemistry, achieving high mechanical, thermal, and chemical stability.

bioRxiv · Nov 3, 2025 · PreprintBiophysics

Discovery of a Heparan Sulfate Binding Domain in Monkeypox Virus H3 as an Anti-poxviral Drug Target Combining AI and MD Simulations

Bin Zheng, Meimei Duan, Yifen Huang, Shangchen Wang, Jun Qiu, Zhuojian Lu, Lichao Liu, Guojin Tang, Lin Cheng, Peng Zheng

The paper identifies a conserved heparan sulfate binding domain in MPXV H3 using AI and MD simulations, validates its role in viral adhesion, and demonstrates a protein inhibitor that disrupts this interaction, inhibiting infection in vitro and in vivo.

eLife · Aug 13, 2024Peer-reviewedBiophysics