Author

Yifen Huang

Nanjing University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Organism:multiple species· 1 Assay:protein structure· 1

Frequent Co-Authors

Bin ZhengiD· 1 shared Guojin Tang· 1 shared Jun QiuiD· 1 shared Lichao LiuiD· 1 shared Lin ChengiD· 1 shared Meimei Duan· 1 shared Peng ZhengiD· 1 shared Shangchen Wang· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Bin ZhengORCID

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1 paper

Recent·Most cited

Discovery of a Heparan Sulfate Binding Domain in Monkeypox Virus H3 as an Anti-poxviral Drug Target Combining AI and MD Simulations

Bin Zheng, Meimei Duan, Yifen Huang, Shangchen Wang, Jun Qiu, Zhuojian Lu, Lichao Liu, Guojin Tang, Lin Cheng, Peng Zheng

The paper identifies a conserved heparan sulfate binding domain in MPXV H3 using AI and MD simulations, validates its role in viral adhesion, and demonstrates a protein inhibitor that disrupts this interaction, inhibiting infection in vitro and in vivo.

eLife · Aug 13, 2024Peer-reviewedBiophysics