Author

Guoqin Sang

SeekGene BioSciences Co. Ltd., Beijing, China;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:long-read sequencing· 1 Research Focus:trajectory inference· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Yuyan Gong· 2 shared Chuyuan Lou· 1 shared Dan Xu· 1 shared Deyu MengiD· 1 shared Guangxin ZhangiD· 1 shared Huanhuan ShiiD· 1 shared Hui Lin· 1 shared Jiacheng SuniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Yuyan Gong

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2 papers

Recent·Most cited

Cellular context shapes the transcriptomic impact of somatic variants

Peisen Sun, Peng Jia, Chuyuan Lou, Xiaona Li, Miaojing Li, Ruifen Zhang, Hui Lin, Xiujuan Li, Yunsong Zhou, Shuzheng Cai, Zexin Zhang, Pengyu Zhang, Tun Xu, Songbo Wang, Yudong Wang, , Kai Ye

The paper shows that somatic variants' transcriptomic impact depends on cellular context, not just sequence, using single-cell transcriptomics and new tools.

bioRxiv · Nov 2, 2026 · PreprintGenetics

High throughput detection of variation in single-cell whole transcriptome through streamlined scFAST-seq

Guoqin Sang, Jiaxin Chen, Meng Zhao, Huanhuan Shi, Jinhuan Han, Jiacheng Sun, Ying Guan, Xingyong Ma, Guangxin Zhang, Yuyan Gong, Yi Chen Zhao, Shaozhuo Jiao

This paper introduces scFAST-seq, a high-throughput single-cell full-length RNA sequencing method that improves detection of non-polyadenylated transcripts and RNA velocity, and enables simultaneous mutation and cellular status identification in tumor cells.

bioRxiv · Mar 19, 2023 · PreprintGenomics