Author

Guoquan Yan

Fudan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Pengyuan YangiD· 3 shared Mengxi WuiD· 2 shared Mingqi LiuiD· 2 shared Siyuan KongiD· 2 shared Weiqian CaoiD· 2 shared Biyun JiangiD· 1 shared Chao LiuiD· 1 shared Huali SheniD· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersSystems Biology

Pengyuan YangORCID

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3 papers

Recent·Most cited

pGlycoQuant with a deep residual network for precise and minuscule-missing-value quantitative glycoproteomics enabling the functional exploration of site-specific glycosylation

Weiqian Cao, Siyuan Kong, Wenfeng Zeng, Pengyun Gong, Biyun Jiang, Xinhang Hou, Yang Zhang, Huanhuan Zhao, Mingqi Liu, Xihua Qiao, Mengxi Wu, Guoquan Yan, Chao Liu, Pengyuan Yang

pGlycoQuant is a tool for quantitative glycopeptide analysis that reduces missing values using a deep residual network, enabling site-specific glycosylation studies in hepatocellular carcinoma.

bioRxiv · Nov 15, 2021 · PreprintSystems Biology

GproDIA enables data-independent acquisition glycoproteomics with comprehensive statistical control

Yi Yang, Guoquan Yan, Siyuan Kong, Mengxi Wu, Pengyuan Yang, Weiqian Cao, Liang Qiao

GproDIA improves glycoproteomics by enabling accurate glycopeptide identification and quantification using DIA data with comprehensive statistical control.

Nature Communications · Oct 18, 2021Peer-reviewedBioinformatics

Multilayered N-glycoproteomics reveals impaired N-glycosylation promoting Alzheimer’s disease

Pan Fang, Juanjuan Xie, Shaoming Sang, Lei Zhang, Mingqi Liu, Lujie Yang, Yiteng Xu, Guoquan Yan, Jun Hu Yao, Xing Gao, Wen‐Jing Qian, Zhongfeng Wang, Yang Zhang, Pengyuan Yang, Huali Shen

This study uses multilayered N-glycoproteomics to show impaired N-glycosylation in Alzheimer's disease mouse models, affecting protein function and neuronal health.

Analytical Chemistry · Nov 21, 2019Peer-reviewedSystems Biology