Synthesis, Biological Activity and Molecular Docking of New Tricyclic Series as α-glucosidase Inhibitors
H. A. Abuelizz, N. A. Iwana, R. Ahmad, A. El-Hassane, M. Marzouk, R. Al-Salahi
The paper synthesizes and evaluates 25 tricyclic compounds as α-glucosidase inhibitors, finding that compound 6h has stronger activity than acarbose with an IC50 of 104.07 mM.
bioRxiv · May 23, 2018Biochemistry