R. Ahmad

Detection of pathogens and antimicrobial resistant genes from urine within 5 hours using Nanopore sequencing

This study demonstrates rapid detection of pathogens and antimicrobial resistance genes in urine using Nanopore sequencing within five hours.

Long-term hematopoietic stem cells trigger quiescence in Leishmania parasites

This study shows that Leishmania parasites enter quiescence after 4-6 divisions in hematopoietic stem cells, enabling drug resistance and increased infectivity.

Glucose intolerance induces anxiety-like behaviors independent of obesity and insulin resistance in a novel model of nutritional metabolic stress

This study shows glucose intolerance can cause anxiety-like behaviors without obesity or insulin resistance, using a new nutritional model of metabolic stress.

Inflammation causes insulin resistance via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels

This study identifies the IRF3/AIG1 axis in adipocytes as a mechanism linking obesity-induced inflammation to insulin resistance and suggests AIG1 inhibition as a therapeutic approach.

ANGPTL8 R59W variant influences inflammation through modulating NF-κB pathway under TNFα stimulation

This study shows the ANGPTL8 R59W variant increases TNF and IL7 levels and NF-κB activity through altered binding dynamics.

A novel, precise and high-throughput technology for viroid detection in cannabis (MFDetectTM)

This paper introduces MFDetectTM, a high-throughput viroid detection method for cannabis, showing it is comparable to RT-PCR and suitable for early HLVd detection in various plant tissues.

SERS nanowire chip and machine learning enabled instant identification and classification of clinically relevant wild-type and antibiotic resistant bacteria at species and strain level

This paper develops a SERS chip combined with machine learning to rapidly identify and classify bacteria at species and strain levels, including antibiotic-resistant strains.

Gut Microbiome Prediction: From Current Human Evidence to Future Possibilities

This study identifies geographic variations in gut microbiomes across India, UAE, and Singapore and demonstrates the predictive accuracy of a proprietary algorithm for disease risk and wellness outcomes.

Highly sensitive quantitative phase microscopy and deep learning complement whole genome sequencing for rapid detection of infection and antimicrobial resistance

This paper combines quantitative phase microscopy and deep learning with whole-genome sequencing to rapidly detect infections and antimicrobial resistance in clinical samples.

Multi-excitation Raman Spectroscopy Complements Whole Genome Sequencing for Rapid Detection of Bacterial Infection and Resistance in WHO Priority Pathogens

This paper combines multi-excitation Raman spectroscopy with whole-genome sequencing to rapidly detect bacterial infections and resistance in WHO priority pathogens, achieving high accuracy in classification.

A glycerol shunt functions as a glucose excess security valve in pancreatic β-cells

This study identifies a glycerol shunt in pancreatic β-cells that mitigates glucose excess by diverting glucose carbons to glycerol production, thereby preventing insulin hypersecretion and glucotoxicity.

Bio-hybrid micro-swimmers propelled by flagella isolated from C. reinhardtii

This paper constructs bio-hybrid micro-swimmers using flagella from C. reinhardtii and shows their motion depends on calcium concentration, with higher concentrations enabling faster, straight-line movement.

Time-reversal symmetric component of the flagellar beat enhances the translational and rotational velocities of isolated Chlamydomonas flagella

This study identifies two additional modes in Chlamydomonas flagellar beating that enhance translational and rotational velocities by approximately a factor of 2.

Light-powered reactivation of flagella and contraction of microtubules network: towards building an artificial cell

This paper demonstrates a light-powered artificial system that integrates photosynthetic vesicles with flagella to control ATP synthesis and microtubule contraction in cell-like compartments.

Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α

This study shows that nSMase2 regulates TNF-α-induced inflammatory responses in monocytes/macrophages by affecting CD11c expression and inflammatory mediator secretion.

Crocus Sativus and Its Active Compound, Crocin Inhibits the Endothelial Activation and Monocyte-Endothelial Cells Interaction in Stimulated Human Coronary Artery Endothelial Cells

This study shows that saffron and its compound crocin inhibit endothelial activation and monocyte-endothelial cell interactions in LPS-stimulated HCAECs.

The association of self-reported sleep quality and obesity in Kuwait using the Pittsburgh Sleep Quality Index (PSQI)

This study investigates the association between self-reported sleep quality and obesity in Kuwait using the Pittsburgh Sleep Quality Index (PSQI) in a cross-sectional survey of 1002 participants.

Bioactivity-guided isolation of rosmarinic acid as a principle bioactive compound from the butanol extract of Isodon rugosus against pea aphid, Acyrthosiphon pisum

This study isolates rosmarinic acid from Isodon rugosus as a bioactive compound with insecticidal activity against pea aphids, showing potential as a safer alternative to synthetic pesticides.

Synthesis, Biological Activity and Molecular Docking of New Tricyclic Series as α-glucosidase Inhibitors

The paper synthesizes and evaluates 25 tricyclic compounds as α-glucosidase inhibitors, finding that compound 6h has stronger activity than acarbose with an IC50 of 104.07 mM.